Watch My Sister's Keeper for Free: How to Stream the Movie Online at 123Movies. . Sara and Brian live an idyllic life with their young son and daughter. But their family is rocked by sudden, heartbreaking news that forces them to make a difficult and unorthodox choice in order to save their baby girl's life. The parents' desperate decision raises both ethical and moral questions and rips away at the foundation of their relationship. Their actions ultimately set off a court case that threatens to tear the family apart, while revealing surprising truths that challenge everyone's perceptions of love and loyalty and give new meaning to the definition of healing.